Dexbrompheniramine (maleate), CAS [[2391-03-9]]

Product Overview

• Article Name: Dexbrompheniramine (maleate), CAS [[2391-03-9]]
• Biozol Catalog Number: MCE-HY-A0191A
• Supplier Catalog Number: HY-A0191A
• Alternative Catalog Number: MCE-HY-A0191A-10MG,MCE-HY-A0191A-5MG,MCE-HY-A0191A-50MG,MCE-HY-A0191A-25MG,MCE-HY-A0191A-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: (+)-Brompheniramine (maleate), (S)-Brompheniramine (maleate)

Product Description

Dexbrompheniramine ((+)-Brompheniramine, (S)-Brompheniramine) maleate is a dual inhibitor of histamine H1 receptor and TRPV1 receptor that can cross the blood-brain barrier. Dexbrompheniramine maleate exerts its effects by functionally blocking H1 receptor activity and dose-dependently inhibiting TRPV1-mediated calcium responses, including Capsaicin (HY-10448)-induced responses. The combination of Dexbrompheniramine maleate with Cimetidine (HY-14289) eliminates histamine-induced and sham-feeding-induced drinking behavior, whereas Dexbrompheniramine maleate alone does not induce thirst or alter sham-feeding behavior in rats. Dexbrompheniramine maleate can be used in the research of chronic cough and related pathological mechanisms[1][2][3].

Product Properties

• Molecular Weight: 435.31
• CAS Number: [2391-03-9]
• Formula: C20H23BrN2O4
• Target: Histamine Receptor,TRP Channel

Application Notes

• Application Notes: MCE Product type: Reference compound