Clomiphene (Clomifene, (Z/E)-Enclomiphene, (Z/E)-Enclomifene) is an orally active ovulation-inducing agent. Clomiphene binds to hypothalamic estrogen receptors to elevate FSH levels, and exhibits antiestrogenic or estrogenic properties. Clomiphene can induce erturbations during meiotic maturation and cytogenetic abnormalities in mouse oocytes. Clomiphene ameliorates memory impairment in PCOS models. Clomiphene mobilizes cytosolic calcium and reduces viability in prostate cancer cells. Clomiphene can be used for the research of polycystic ovary syndrome (PCOS) and prostate cancer[1][2][3][4].
Molecular Weight:
405.96
CAS Number:
[911-45-5]
Formula:
C26H28ClNO
Target:
Estrogen Receptor/ERR
Application Notes:
MCE Product type: Reference compound
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