Clomiphene (Clomifene, (Z/E)-Enclomiphene, (Z/E)-Enclomifene) hydrochloride is an orally active ovulation-inducing agent. Clomiphene hydrochloride binds to hypothalamic estrogen receptors to elevate FSH levels, and exhibits antiestrogenic or estrogenic properties. Clomiphene hydrochloride can induce erturbations during meiotic maturation and cytogenetic abnormalities in mouse oocytes. Clomiphene hydrochloride ameliorates memory impairment in PCOS models. Clomiphene hydrochloride mobilizes cytosolic calcium and reduces viability in prostate cancer cells. Clomiphene hydrochloride can be used for the research of polycystic ovary syndrome (PCOS) and prostate cancer[1][2][3][4].
Molecular Weight:
442.42
CAS Number:
[57049-00-0]
Formula:
C26H29Cl2NO
Target:
Estrogen Receptor/ERR
Application Notes:
MCE Product type: Reference compound
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