Ondansetron (GR 38032, SN 307) hydrochloride is a highly selective 5-HT3 receptor antagonist with an IC50 value of 103 pM. Ondansetron hydrochloride exerts its antiemetic effect by antagonizing 5-HT receptors located in localized neurons in the peripheral and central nervous systems. Ondansetron hydrochloride can inhibit nausea and vomiting induced by chemotherapy and radiotherapy[1][2][3][4][5][6][7][8].
Molecular Weight:
329.82
Purity:
99.94
CAS Number:
[99614-01-4]
Formula:
C18H20ClN3O
Target:
5-HT Receptor
Application Notes:
MCE Product type: Reference compound
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