Doxofylline is an orally active PDE IV inhibitor and A1AR antagonist. Doxofylline reduces inflammation in epithelial cells via inhibiting mitochondrial ROS production and amelioration of multiple cellular pathways (NLRP3-TXNIP inflammasome activation). Doxophylline can be used in studies of asthma, chronic obstructive pulmonary disease, and bronchospasm[1][2][3].
Molecular Weight:
266.25
Purity:
99.97
CAS Number:
[69975-86-6]
Formula:
C11H14N4O4
Target:
Adenosine Receptor,Phosphodiesterase (PDE),Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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