Quetiapine hemifumarate is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine hemifumarate is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine hemifumarate has moderate to high affinity for the human D2, HT1A, 5-HT2A, 5-HT2C receptor with pKis of 7.25, 5.74, 7.54, 5.55. Antidepressant and anxiolytic effects[1].
Molecular Weight:
441.54
Purity:
99.96
CAS Number:
[111974-72-2]
Formula:
C23H27N3O4S
Target:
5-HT Receptor,Dopamine Receptor
Application Notes:
MCE Product type: Reference compound
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