Adapalene (CD271), a third-generation synthetic retinoid, is widely used for the research of acne. Adapalene is a potent RAR agonist, with AC50s of 2.3 nM, 9.3 nM, and 22 nM for RARbeta, RARgamma, RARalpha, respectively. Adapalene also inhibits the enzymatic activity of GOT1 in a non-competitive manner. Adapalene exhibits anti-tumor activity[1][2][3].
Molecular Weight:
412.52
Purity:
99.94
CAS Number:
[106685-40-9]
Formula:
C28H28O3
Target:
Apoptosis,Autophagy,RAR/RXR
Application Notes:
MCE Product type: Reference compound
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