Adapalene (CD271) sodium salt, a third-generation synthetic retinoid, is widely used for the research of acne. Adapalene sodium salt is a potent RAR agonist, with AC50s of 2.3 nM, 9.3 nM, and 22 nM for RARbeta, RARgamma, RARalpha, respectively. Adapalene sodium salt also inhibits the enzymatic activity of GOT1 in a non-competitive manner. Adapalene sodium salt exhibits anti-tumor activity[1][2][3].
Molecular Weight:
434.50
Purity:
99.69
CAS Number:
[911110-93-5]
Formula:
C28H27NaO3
Target:
Apoptosis,Autophagy,RAR/RXR
Application Notes:
MCE Product type: Reference compound
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