Levoketoconazole ((-)-Ketoconazole) is the 2S,4R enantiomer derived from racemic Ketoconazole (HY-B0105). Levoketoconazole is a potent and orally active cortisol synthesis inhibitor. Levoketoconazole inhibits key steps in cortisol and testosterone synthesis by inhibiting CYP11B1, CYP11A1, and CYP17A1. Levoketoconazole can be used for research on endogenous Cushings syndrome[1][2].
Molecular Weight:
531.43
Purity:
99.71
CAS Number:
[142128-57-2]
Formula:
C26H28Cl2N4O4
Target:
Cytochrome P450
Application Notes:
MCE Product type: Reference compound
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