Omeprazole sulfone (methoxy-d3), CAS [[1189891-71-1]]
Biozol Catalog Number:
MCE-HY-B0113S2
Supplier Catalog Number:
HY-B0113S2
Alternative Catalog Number:
MCE-HY-B0113S2-1MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
Omeprazole sulphone (methoxy-d3)
Omeprazole sulfone (methoxy-d3) is the deuterium labeled Omeprazole sulfone. Omeprazole sulfone (H 16868) is an orally active H+,K+-ATPase inhibitor and a proton pump inhibitor. Omeprazole sulfone competitively inhibits CYP2C19, CYP3A4, and CYP2C9 activity. Omeprazole sulfone inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole sulfone inhibits pancreatic cancer cell proliferation, induces apoptosis, autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole sulfone alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole sulfone aslo has neuroprotective and antibacterial effects[1][2][3][4][5].