Furosemide is a potent and orally active inhibitor of Na+/K+/2Cl- (NKCC) cotransporter, NKCC1 and NKCC2[1]. Furosemide is also a GABAA receptors antagonist and displays 100-fold selectivity for alpha6-containing receptors than alpha1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema[2].
Molecular Weight:
330.74
Purity:
99.83
CAS Number:
[54-31-9]
Formula:
C12H11ClN2O5S
Target:
GABA Receptor,NKCC
Application Notes:
Reference compound
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