Vicriviroc (SCH 417690) malate is an orally active CCR5 antagonist with the IC50 of 10 nM, and also inhibts MIP-1alpha and intracellular calcium release induced by the ligand RANTES (10 nM) with the IC50 values of 0.91 nM and 16 nM,,respectively. Vicriviroc malate can inhibits human immunodeficiency virus type 1 (HIV-1) infection, and can also used for study of cancer[1][2].
Molecular Weight:
667.72
CAS Number:
[541503-81-5]
Formula:
C32H44F3N5O7
Target:
CCR,HIV
Application Notes:
Reference compound
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