Mianserin hydrochloride (Org GB 94) is an orally active H1 receptor antagonist. Mianserin hydrochloride can activate kappa-opioid receptor and octopamine recepto. Mianserin hydrochloride increases ERK1/2 and CREB phosphorylation, and antagonizes full kappa-opioid agonist and dynorphin A-induced MAPK phosphorylation. Mianserin hydrochloride modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin hydrochloride can be used for the research of neurological disease, such as depression and epilepsy[1][2][3][4][5].
Molecular Weight:
300.83
Purity:
99.95
CAS Number:
[21535-47-7]
Formula:
C18H21ClN2
Target:
ERK,Histamine Receptor,Opioid Receptor,p38 MAPK
Application Notes:
MCE Product type: Natural Products
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