Mianserin hydrochloride (Org GB 94) (Standard) is the analytical standard of Mianserin hydrochloride. This product is intended for research and analytical applications. Mianserin hydrochloride is an orally active H1 receptor antagonist. Mianserin hydrochloride can activate kappa-opioid receptor and octopamine recepto. Mianserin hydrochloride increases ERK1/2 and CREB phosphorylation, and antagonizes full kappa-opioid agonist and dynorphin A-induced MAPK phosphorylation. Mianserin hydrochloride modulates social and exploratory behaviour, raises electroconvulsive thresholds. Mianserin hydrochloride can be used for the research of neurological disease, such as depression and epilepsy[1][2][3][4][5].
