Mycophenolate mofetil (hydrochloride), CAS [[116680-01-4]]
Biozol Catalog Number:
MCE-HY-B0199A
Supplier Catalog Number:
HY-B0199A
Alternative Catalog Number:
MCE-HY-B0199A-50MG,MCE-HY-B0199A-100MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
RS 61443 (hydrochloride), TM-MMF (hydrochloride)
Mycophenolate mofetil (RS 61443, TM-MMF) hydrochloride is an orally active antimetabolic immunosuppressant with antiproliferative and anti-inflammatory properties. Mycophenolate mofetil hydrochloride significantly inhibits the production of B, T lymphocytes and the proliferation of smooth muscle cells by selectively blocking the de novo purine synthesis pathway. Mycophenolate mofetil hydrochloride effectively reduces adventitial inflammation, medial necrosis and intimal thickening in rat aortic allografts, and decreases the number of lymphocytes expressing the IL-2 receptor, thereby delaying xenograft rejection. Mycophenolate mofetil hydrochloride shows certain toxicity in a hamster-to-rat limb xenotransplantation model when used in combination with FK506 (HY-13756). Mycophenolate mofetil hydrochloride is widely used in studies related to allograft arteriosclerosis (chronic rejection)[1][2].
Molecular Weight:
469.96
Purity:
99.17
CAS Number:
[116680-01-4]
Formula:
C23H32ClNO7
Target:
Interleukin Related
Application Notes:
MCE Product type: Reference compound
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