Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-beta/Smad signaling pathway. Hydrochlorothiazide has direct vascular relaxant effects via opening of the calcium-activated potassium (KCA) channel. Hydrochlorothiazide improves cardiac function, reduces fibrosis and has antihypertensive effect[1][2][3].
Molecular Weight:
297.75
Purity:
99.46
CAS Number:
[58-93-5]
Formula:
C7H8ClN3O4S2
Target:
Potassium Channel,TGF-beta/Smad
Application Notes:
MCE Product type: Reference compound
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