Enoxacin (AT 2266), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml). Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing[1][2][3][4].
Molecular Weight:
320.32
Purity:
98.67
CAS Number:
[74011-58-8]
Formula:
C15H17FN4O3
Target:
Antibiotic,Bacterial,DNA/RNA Synthesis,MicroRNA
Application Notes:
MCE Product type: Reference compound
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