Enoxacin hydrate (Enoxacin sesquihydrate), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml). Enoxacin hydrate is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin hydrate has potent activities against gram-positive and -negative bacteria. Enoxacin hydrate is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing[1][2][3][4].
Molecular Weight:
347.34
Purity:
98.51
CAS Number:
[84294-96-2]
Formula:
C15H17FN4O3.3/2H2O
Target:
Antibiotic,Bacterial,DNA/RNA Synthesis,MicroRNA
Application Notes:
MCE Product type: Reference compound
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