Gabexate (mesylate) (Standard) is the analytical standard of Gabexate (mesylate). This product is intended for research and analytical applications. Gabexate mesylate (FOY) is is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. Gabexate mesylate inhibits human thrombin, urokinase, plasmin, and Factor Xa with Kis of 0.97, 1.3, 1.6, and 8.5 µM, respectively. Gabexate mesylate binds to human and bovine tryptase with Kis of 3.4 nM and 18 µM, respectively. Gabexate mesylate exerts an anticoagulant effect on the clotting activity of thrombin and has anti-inflammatory effect by viainhibition of NF-kappaB, proinflammatory cytokines, and nitric oxide. Gabexate mesylate is used for pancreatitis and disseminated intravascular coagulation[1][2][3][4].
Molecular Weight:
417.48
CAS Number:
[56974-61-9]
Formula:
C17H27N3O7S
Target:
Factor Xa,Proteasome,Reference Standards
Application Notes:
MCE Product type: Reference Standards
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