Miglitol (BAY-m1099) is an orally active antidiabetic compound that inhibits the breakdown of glycoconjugates into glucose. Miglitol inhibits glycoside hydrolase enzymes called alpha-glucosidases. Miglitol inhibits oxidative stress-induced apoptosis and mitochondrial ROS over-production in endothelial cells by enhancement of AMP-activated protein kinase. Dietary supplementation with Miglitol from pre-onset stage in OLETF rats delays the onset and development of diabetes and preserves the insulin secretory function of pancreatic islets[1][2][3][4].
Molecular Weight:
207.22
Purity:
98
CAS Number:
[72432-03-2]
Formula:
C8H17NO5
Target:
AMPK,Glycosidase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound1
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