Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect[1].
Molecular Weight:
361.39
Purity:
99.71
CAS Number:
[603-50-9]
Formula:
C22H19NO4
Target:
Dopamine Transporter,Opioid Receptor
Application Notes:
MCE Product type: Reference compound
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