Ropivacain is a potent sodium channel blocker. Ropivacain blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese[1][2]. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 µM in COS-7 cells membrane[3]. Ropivacaine is used for the research of neuropathic pain management[1].
Molecular Weight:
274.40
Purity:
99.98
CAS Number:
[84057-95-4]
Formula:
C17H26N2O
Target:
Potassium Channel,Sodium Channel
Application Notes:
MCE Product type: Reference compound
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