Nitisinone is an orally active, competitive and reversible 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor with an IC50 of 173 nM. Nitisinone promotes tyrosine accumulation in a dose-dependent manner. nitisinone can be used in studies of hereditary tyrosinemia type 1 (HT-1) (a rare genetic disorder) and albinism[1][2][3][4].
Molecular Weight:
329.23
Purity:
99.93
CAS Number:
[104206-65-7]
Formula:
C14H10F3NO5
Target:
HPPD
Application Notes:
MCE Product type: Reference compound
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