(S)-Lercanidipine, CAS [[185197-71-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-B0612B
Supplier Catalog Number:
HY-B0612B
Alternative Catalog Number:
MCE-HY-B0612B-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
(S)-Lercanidipine is a calcium channel blocker with antihypertensive and neuroprotective activities. (S)-Lercanidipine reduces oxidative stress and protects auditory sensory hair cells from noise-induced damage. (S)-Lercanidipine showed significant protective effects on cell viability in in vitro experiments, especially at low concentrations. (S)-Lercanidipine has been found to effectively reduce the hearing threshold of mice after noise stimulation and protect the survival of outer hair cells. The antioxidant properties of (S)-Lercanidipine are reflected in its increased expression of antioxidant enzyme genes and decreased expression of oxidative enzyme genes. (S)-Lercanidipine administration is effective in reducing noise-induced hearing loss both before and after noise exposure. (S)-Lercanidipine may alleviate noise-induced hearing loss and protect the survival of outer hair cells through its antioxidant mechanism[1].
Molecular Weight:
611.73
CAS Number:
[185197-71-1]
Formula:
C36H41N3O6
Target:
Calcium Channel,Sodium Channel
Application Notes:
MCE Product type: Reference compound
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