Amifostine (WR2721) is a broad-spectrum cytoprotective agent and a radioprotector. Amifostine selectively protects normal tissues from damage caused by radiation and chemotherapy. Amifostine is potent hypoxia-inducible factor-alpha1 (HIF-alpha1) and p53 inducer. Amifostine protects cells from damage by scavenging oxygen-derived free radicals. Amifostine reduces renal toxicity and has antiangiogenic action[1][2][3][4].
Molecular Weight:
214.22
Purity:
99.95
CAS Number:
[20537-88-6]
Formula:
C5H15N2O3PS
Target:
HIF/HIF Prolyl-Hydroxylase,MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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