Cefepime (BMY-28142) is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC50 of 21.115 mM and a Ki of 35.092 mM. Cefepime inhibits hPON1 via a non-competitive mechanism and blocks GABAA receptors. Cefepime penetrates the outer membrane of Gram-negative bacteria, inhibits the growth of Gram-positive and Gram-negative bacteria, and does not induce the production of beta-lactamase[1][2][3][4].
Molecular Weight:
480.56
Purity:
99.86
CAS Number:
[88040-23-7]
Formula:
C19H24N6O5S2
Target:
Antibiotic,Bacterial,GABA Receptor
Application Notes:
MCE Product type: Reference compound
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