beta-Estradiol 17-acetate (1,3,5(10)-Estratriene-3,17beta-diol 17-acetate) is a long-acting endogenous estrogen precursor and also a cell viability and proliferation enhancer. beta-Estradiol 17-acetate promotes the adhesion and proliferation of freshly isolated and revived female-derived human brain microvascular endothelial cells, and reverses the decreased viability of revived male-derived human brain microvascular endothelial cells. beta-Estradiol 17-acetate exerts the microvascular protective effect of estrogen, enabling non-tumor human brain microvascular endothelial cells to be cultured in vitro for 2 months after cryopreservation. beta-Estradiol 17-acetate is biotransformed into beta-estradiol via hydrolase action in the in vitro skin of humans, hairless dogs, rats and hairless mice[1][2].
Molecular Weight:
314.42
Purity:
99.93
CAS Number:
[1743-60-8]
Formula:
C20H26O3
Target:
Estrogen Receptor/ERR
Application Notes:
MCE Product type: Natural Products
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