Doxepin hydrochloride is an orally active tricyclic antidepressant agent. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2[1][2]. Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant[3].. Doxepin has therapeutic effects in atopic dermatitis,chronic urticarial,can improve cognitive processes, protect central nervous system[4].. Doxepin has also been proposed as a protective factor against oxidative stress[5]..
Molecular Weight:
315.84
Purity:
99.84
CAS Number:
[1229-29-4]
Formula:
C19H22ClNO
Target:
Cytochrome P450,Histamine Receptor
Application Notes:
MCE Product type: Reference compound
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