Hydroxyprogesterone caproate (17alpha-Hydroxyprogesterone hexanoate, 17alpha-Hydroxyprogesterone caproate) is a progesterone receptor (progesterone receptor) ligand and steroid hormone transcription inhibitor. Hydroxyprogesterone caproate downregulates estrogen receptors in target tissues and activates their metabolic pathways, and exhibits equivalent affinity for progesterone receptor A and progesterone receptor B. Hydroxyprogesterone caproate shows no consistent teratogenicity or developmental toxicity in rat, mouse and monkey models, but induces resorption or abortion in rhesus monkeys at human-equivalent doses. Hydroxyprogesterone caproate promotes the production of TNF-alpha in lipopolysaccharide-stimulated whole blood from non-pregnant women. Hydroxyprogesterone caproate can be used in scientific research related to preterm birth[1][2].
Molecular Weight:
428.60
Purity:
99.29
CAS Number:
[630-56-8]
Formula:
C27H40O4
Target:
Progesterone Receptor
Application Notes:
MCE Product type: Reference compound
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