Seratrodast (AA 2414), an orally active antiasthmatic agent, is a thromboxane A2 receptor (TP) antagonist and ferroptosis inhibitor. Seratrodast reduces lipid ROS production, modulates the systemic xc-/GSH/GPX4 axis, and inhibits JNK phosphorylation and p53 expression. Seratrodast exhibits anti-asthmatic and anti-epileptic activity[1][2][3].
Molecular Weight:
354.44
Purity:
99.59
CAS Number:
[112665-43-7]
Formula:
C22H26O4
Target:
Ferroptosis,JNK,MDM-2/p53,Prostaglandin Receptor,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound1
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