Oxaprozin is an orally active and potent COX inhibitor, with IC50 values of 2.2 µM for human platelet COX-1 and and 36 µM for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin also inhibits the activation of NF-kappaB. Oxaprozin induces cell apoptosis. Oxaprozin shows anti-inflammatory activity. Oxaprozin-mediated inhibition of the Akt/IKK/NF-kappaB pathway contributes to its anti-inflammatory properties[1][2].
Molecular Weight:
293.32
Purity:
99.94
CAS Number:
[21256-18-8]
Formula:
C18H15NO3
Target:
Akt,Apoptosis,COX,IKK,NF-kappaB
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
