Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with a Km of 0.592 µM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of beta-naphthoflavone (HY-114740). Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms[1][2].
Molecular Weight:
184.26
Purity:
99.98
CAS Number:
[132-65-0]
Formula:
C12H8S
Target:
Aryl Hydrocarbon Receptor,Cytochrome P450
Application Notes:
MCE Product type: Reference compound
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