Metergoline is a serotonin (5-HT) receptor and dopamine receptors antagonist, with pKis of 8.64, 8.75 and 8.75 for 5-HT2A, 5-HT2B and 5-HT2C, respectively. Metergoline is a high-affinity ligand for the h5-HT7 receptor, with a Ki of 16 nM. Metergoline is also a reversible neural Na+ channels inhibitor. Metergoline is commonly used for the research of seasonal affective disorder, prolactin hormone regulation[1][2][3].
Molecular Weight:
403.52
Purity:
99.94
CAS Number:
[17692-51-2]
Formula:
C25H29N3O2
Target:
5-HT Receptor,Dopamine Receptor,Sodium Channel
Application Notes:
MCE Product type: Reference compound
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