Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent[1].
Molecular Weight:
356.48
Purity:
99.81
CAS Number:
[3105-97-3]
Formula:
C20H24N2O2S
Target:
DNA/RNA Synthesis,Parasite,Topoisomerase
Application Notes:
MCE Product type: Reference compound1
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