Gliquidone can bind to the pancreatic beta-cells and increases insulin release to regulate blood glucose levels. Gliquidone significantly decreases LPS (HY-D1056)-induced proinflammatory responses and inhibits ERK/STAT3/NF-kappaB phosphorylation in BV2 microglial cells. Gliquidone can suppress microgliosis, microglial hypertrophy mediated by LPS, and proinflammatory cytokine COX-2 and IL-6 levels in murine model. Gliquidone also exhibits good anticancer activity in lung carcinoma cells. Gliquidone has antioxidant property. Gliquidone can be studied in research for type 2 diabetes and cancers[1][2].
Molecular Weight:
527.63
Purity:
99.93
CAS Number:
[33342-05-1]
Formula:
C27H33N3O6S
Target:
COX,ERK,Interleukin Related,NF-kappaB,Potassium Channel,Reactive Oxygen Species (ROS),STAT
Application Notes:
MCE Product type: Reference compound
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