Terfenadine, CAS [[50679-08-8]]

Product Overview

• Article Name: Terfenadine, CAS [[50679-08-8]]
• Biozol Catalog Number: MCE-HY-B1193
• Supplier Catalog Number: HY-B1193
• Alternative Catalog Number: MCE-HY-B1193-100MG,MCE-HY-B1193-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: ()-Terfenadine, MDL-991

Product Description

Terfenadine (()-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM[1]. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9[2].

Product Properties

• Molecular Weight: 471.67
• Purity: 99.98
• CAS Number: [50679-08-8]
• Formula: C32H41NO2
• Target: Apoptosis,Caspase,Histamine Receptor,Na+/Ca2+ Exchanger,Potassium Channel

Application Notes

• Application Notes: MCE Product type: Reference compound