Metyrapone (Su-4885) is a potent and orally active 11beta-hydroxylase inhibitor and an autophagy activator, also inhibits the production of aldosterone. Metyrapone inhibits synthesis of endogenous adrenal corticosteroid, decreases glucocorticoid levels, and also affects behavior and emotion. In addition, Metyrapone increases the efficiency of autophagic process via downregulation of mTOR pathway, and interacts with Pseudomonas putida cytochrome P-450. Metyrapone can be used for researching Cushings syndrome and depression[1][2][3][4][5].
Molecular Weight:
226.27
Purity:
99.83
CAS Number:
[54-36-4]
Formula:
C14H14N2O
Target:
Autophagy,Cytochrome P450,Endogenous Metabolite
Application Notes:
MCE Product type: Reference compound
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