Trihexyphenidyl hydrochloride is a selective and orally active M1 muscarinic receptor antagonist with an IC50 of 3.7 nM for rat cerebral cortex M1 muscarinic receptors. Trihexyphenidyl hydrochloride modulates cholinergic activity, countering acetylcholine supersensitivity in neural pathways. Trihexyphenidyl hydrochloride improves movement disorder, inhibits McN-A-343 (HY-107648)-induced pressor responses, vagally-induced bradycardia and vasodilatation. Trihexyphenidyl hydrochloride can be used for the research of Parkinsons disease.[1][2][3].
Molecular Weight:
337.93
Purity:
99.93
CAS Number:
[52-49-3]
Formula:
C20H32ClNO
Target:
Cholinesterase (ChE),mAChR
Application Notes:
MCE Product type: Reference compound
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