Imipramine is an orally active tertiary amine tricyclic antidepressant. Imipramine is a Fascin1 inhibitor with antitumor activities. Imipramine also inhibits serotonin transporter with an IC50 value of 32 nM. Imipramine stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine shows neuroprotective and immunomodulatory effects[1][2][3][4][5].
Molecular Weight:
280.42
Purity:
99.88
CAS Number:
[50-49-7]
Formula:
C19H24N2
Target:
Apoptosis,Autophagy,Serotonin Transporter
Application Notes:
MCE Product type: Reference compound1
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