Picrotoxinin, a potent convulsant, is a chloride channel blocker. Picrotoxinin is a noncompetitive GABAA receptor antagonist, which negatively modulates the action of GABA on GABAA receptors. Picrotoxinin inhibits alpha1beta2gamma2L GABAA receptor with an IC50 of 1.15 µM[1].
Molecular Weight:
292.28
Purity:
99.91
CAS Number:
[17617-45-7]
Formula:
C15H16O6
Target:
Chloride Channel,GABA Receptor
Application Notes:
MCE Product type: Natural Products
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