Benzamil (Benzylamiloride), an Amiloride analogue, is a Na+/Ca2+ exchanger (NCX) inhibitor (IC50~100 nM). Benzamil also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1 µM[1][2][3].
Molecular Weight:
319.75
CAS Number:
[2898-76-2]
Formula:
C13H14ClN7O
Target:
Na+/Ca2+ Exchanger,Sodium Channel
Application Notes:
MCE Product type: Reference compound
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