Malachite green hemioxalate (MCCK1) is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antibacterial activity, which is attributed to inhibition of intracellular enzymes, insertion into DNA and/or interaction with cell membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE, and inhibits its downstream targets such as IkappaBalpha, p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo[1][2][3].
Molecular Weight:
463.50
Purity:
98
CAS Number:
[2437-29-8]
Formula:
C23H25N2.1/2C2H2O4.C2HO4
Target:
Apoptosis,Fungal,IKK,NF-kappaB
Application Notes:
Dye Reagents
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