2-Deoxyguanosine monohydrate is a nucleoside composed of guanine and deoxyribose, and is one of the basic building blocks of DNA. In the oxidation reaction mediated by singlet oxygen 1O2, the guanine base of 2-Deoxyguanosine is easily oxidized to generate two major products, 4,8-dihydro-4-hydroxy-8-oxodG and 7,8-dihydro-8-oxodG. The oxidation products of 2-Deoxyguanosine monohydrate may participate in DNA damage, which may affect gene expression or induce cancer[1].
Molecular Weight:
285.26
Purity:
99.70
CAS Number:
[312693-72-4]
Formula:
C10H15N5O5
Target:
Endogenous Metabolite
Application Notes:
Natural Products
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