N-Ethylmaleimide (NEM) derives from maleic acid, it can alkylates free sulfhydryl. N-Ethylmaleimide is an irreversible cysteine protease inhibitor. N-ethylmaleimide specific inhibits phosphate transport in mitochondria. N-Ethylmaleimide inhibits prolyl endopeptidase with an IC50 value of 6.3 µM. N-Ethylmaleimide can be used to modify cysteine residues in proteins and peptides[1][2][3].
Molecular Weight:
125.13
Purity:
99.97
CAS Number:
[128-53-0]
Formula:
C6H7NO2
Target:
Apoptosis,Cathepsin,Deubiquitinase
Application Notes:
MCE Product type: Reference compound
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