YO-PRO-1 is a non-cell-membrane-penetrating green fluorescent dye. YO-PRO-1 cannot penetrate normal cell membranes but can penetrate the membranes of apoptotic and necrotic cells. YO-PRO-1 has a high affinity for DNA. When it is not bound to DNA, it emits almost no fluorescence, and when it binds to DNA, it can emit green fluorescence (Ex/Em: 488/53030 nM). YO-PRO-1 is often used together with Propidium Iodide (HY-D0815) to analyze and identify apoptotic and necrotic cells[1][2].
Molecular Weight:
629.32
Purity:
98.20
CAS Number:
[152068-09-2]
Formula:
C24H29I2N3O
Target:
Fluorescent Dye
Application Notes:
MCE Product type: Dye Reagents
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