NF279 is a potent selective and reversible P2X1 receptor antagonist, with an IC50 of 19 nM. NF279 displays good selectivity over P2X2, P2X3 (IC50=1.62 µM), P2X4 (IC50>300 µM). NF279 is a dual HIV-1 coreceptor inhibitor that interferes with the functional engagement of CCR5 and CXCR4 by Env[1][2].
Molecular Weight:
1401.12
Purity:
98.5
CAS Number:
[202983-32-2]
Formula:
C49H30N6Na6O23S6
Target:
HIV,P2X Receptor
Application Notes:
MCE Product type: Reference compound
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