EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA (HY-Y0682). Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation[1][2].
Molecular Weight:
580.49
Purity:
98
CAS Number:
[162303-59-5]
Formula:
C22H32N2O16
Target:
Biochemical Assay Reagents,Mitosis
Application Notes:
MCE Product type: Dye Reagents
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