IR-58, a mitochondria-targeting near-infrared (NIR) fluorophore, is an autophagy enhancer. IR-58 kills tumour cells and induces apoptosis via inducing excessive autophagy, which is mediated through the reactive oxygen species (ROS)-Akt-mTOR pathway[1].
Molecular Weight:
1046.65
CAS Number:
[2374274-85-6]
Formula:
C58H82BrClN4O6
Target:
Apoptosis,Autophagy
Application Notes:
MCE Product type: Dye Reagents
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