CAQ is a near-infrared fluorescent probe based on a curcumin scaffold (Ex/Em = 565/635). CAQ exhibits high affinity for Abeta1-42 aggregates (Kd = 78.89 nM) and excellent selectivity toward common biomolecules. CAQs emission wavelength shows significant solvent dependence. CAQ, by incorporating intramolecular rotation donors and quinoline functional groups, can be used for the specific detection and imaging of Abeta aggregates in Alzheimers disease[1].
Molecular Weight:
418.24
Formula:
C24H21BF2N2O2
Target:
Fluorescent Dye
Application Notes:
MCE Product type: Dye Reagents
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