M-H2S is an endoplasmic reticulum-targeted ratio-type near-infrared fluorescent probe (Ex/Em : 480 nm/560 nm) specifically designed for the detection of hydrogen sulfide (H2S) in living cells and zebrafish. M-H2S exhibits detection limit for H2S of 39.1 nM, and the fluorescence intensity ratio (F650/F560) within the range of 0-40 µM shows a linear relationship with the H2S concentration. M-H2S responds best under pH = 7.2 (the normal physiological pH of the endoplasmic reticulum) conditions, making it suitable for the detection of the microenvironment of the endoplasmic reticulum. M-H2S can be used to study the role of H2S in endoplasmic reticulum function, stress response, and related diseases[1].
Molecular Weight:
422.48
CAS Number:
[2522921-17-9]
Formula:
C27H22N2O3
Target:
Fluorescent Dye
Application Notes:
MCE Product type: Dye Reagents
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